One of several editions of a long list of testimonials, letters, certificats, and even hearsay attesting to the virtues of the so-called poudre d'Irroé, a purgative and laxative preparation invented by Monier, Baron de Taillades, an Avignon physician, with the assistance of Charles Irroé, a Catholic priest with an interest in pharmacy. Irroé's powder, a reddish "balsamic" substance comprised of unknown ingredients, was first marketed in the late 1750s in Avignon, and soon gained a national reputation for success; by 1765 enough praise for the preparation had accumulated that enterprising publishers began regularly printing a list of letters and testimonials by relieved sufferers. These lists grew in length through the 1770s, and included far-flung commendations (ours bears a glowing endorsement for Irroé's powder by a négociant in Basse-Terre, on the Caribbean island of Guadeloupe), and were even translated into German, English, and Spanish. Irroé's powder was originally indicated for a variety of digestive distresses, but it clearly grew over the years into a kind of catholicon, with testimonials from people who claimed it cured fevers, rheumatism, hemophilia, and even cancers. Irroé's powder lost popularity in the 1780s, and vanished from the market by the advent of the Revolution. Our edition is known in a single institutional exemplar, at the Académie nationale de médecine de France.
12mo, 149 x 94 x 2 mm. A12, B6. 35,  pp. Nested quires, with gathering B inserted in the center of A, between A6 and A7. Original stab-stitching, outer conjugate frayed at back but stitching holding firm, leaves toned and dusty, wear to edges, a few dog-ears to fore-corners of first and last leaves, final page abraded at tail gutter corner, with loss to printed border.
On recto of final leaf is a spot reserved for local vendors of the poudre d'Irroé to fill in their name and address; ours is attested in ink by one Monsieur Devaux of Limoges. Later label with letter "P" pasted to tail of spine.